Theses from 2009 to now

• Volume of neonatal care and srvival without disability at 2 years in very preterm infants: results of a french national cohort study.  J Pediatr. 2019; 213:22-29.e4.
• Risk factors for very preterm delivery out of a level III maternity unit: The EPIPAGE-2 cohort study. Paediatr Perinat Epidemiol. 2021;694-705.

• Reducing neonatal morbidity by discontinuing oxytocin during the active phase of first stage of labor: a multicenter randomized controlled trial STOPOXY. BMC Pregnancy Childbirth. 2020 Oct 20;20(1):640.
• Contemporary duration of spontaneous labor and association with maternal characteristics: A French national population-based study. Birth. 2020 Dec 4.
• Frequency and determinants of misuse of augmentation of labor in France: A population-based study. PLoS One. 2021 Feb 9;16(2):e0246729.

• Composite neonatal morbidity indicators using hospital discharge data: A systematic review. Paediatr Perinat Epidemiol. 2020 May;34(3):350-365.
• Measuring severe neonatal morbidity using hospital discharge data in France. Paediatr Perinat Epidemiol. 2021 Nov 19. doi: 10.1111/ppe.12816.

• Determinants of the use of non-pharmacological analgesia for labor pain management: a national population-based study. Pain 2020;161:2571-2580.
• Predictors of incomplete maternal satisfaction with neuraxial labor analgesia: a nationwide study. Anaesth Crit Care Pain Med 2021;40:100939. doi: 10.1016/j.accpm.2021.100939.
• Lack of labour pain management: individual and organisational determinants from a nationwide cross-sectional population-based study. Eur J Anesth in press

• Associations between maternal obesity and severe maternal morbidity: Findings from the French EPIMOMS population-based study. Paediatr Perinat Epidemiol. 2019 Jan;33(1):7-16.
• Maternal obesity and severe pre-eclampsia among immigrant women: a mediation analysis. Sci Rep. 2020 Mar 23;10(1):5215.

• Hunting, Sale, and Consumption of Bushmeat Killed by Lead-Based Ammunition in Benin. Int J Environ Res Public Health. 2018 Jun 1;15(6):1140.
• Comparison of growth models to describe growth from birth to 6 years in a Beninese cohort of children with repeated measurements. BMJ Open. 2020 Sep 18;10(9):e035785.
• Follow-Up of Elevated Blood Lead Levels and Sources in a Cohort of Children in Benin. Int J Environ Res Public Health. 2020 Nov 23;17(22):8689.

• Risk of Severe Acute Maternal Morbidity According to Planned Mode of Delivery in Twin Pregnancies. Obstet Gynecol. 2018 Sep;132(3):647-655.
• Severe maternal morbidity by mode of delivery in women with twin pregnancy and planned vaginal delivery. Sci Rep. 2020 Mar 18;10(1):4944.
• Risk factors and high-risk subgroups of severe acute maternal morbidity in twin pregnancy: A population-based study. PLoS One. 2020 Feb 28;15(2):e0229612.
• Increased risk of severe maternal morbidity in women with twin pregnancies resulting from oocyte donation. Hum Reprod. 2020 Aug 1;35(8):1922-1932.

• Epidemiology of community-onset severe bacterial infections in children and its evolution: a population-based study in France. Pediatr Crit Care Med 2020; 2: e325-e332.
• Vaccine-preventable severe morbidity and mortality caused by meningococcus and pneumococcus: A population-based study in France. Paediatr Perinat Epidemiol. 2018 Sep;32(5):442-447.

• Specialist health care services use in a European cohort of infants born very preterm. Dev Med Child Neurol. 2019 Jul;61(7):832-839.
• Parents’ ratings of post-discharge healthcare for their children born very preterm and their suggestions for improvement: a European cohort study. Pediatr Res. 2020 Sep 18.
• Follow-up after very preterm birth in Europe. Arch Dis Child Fetal Neonatal Ed. 2021 Feb 10:fetalneonatal-2020-320823.

• Discrepancies in national time trends of outpatient antibiotic utilization using different measures: a population-based study in France. J Antimicrob Chemother. 2018 May 1;73(5):1395-1401.
• Association between National Treatment Guidelines for Upper Respiratory Tract Infections and Outpatient Pediatric Antibiotic Use in France: An Interrupted Time-Series Analysis. J Pediatr. 2020; 216: 88-94.e4.
• Community antibiotic prescribing for children in France from 2015 to 2017: a cross-sectional national study. J Antimicrob Chemother. 2020 Aug 1;75(8):2344-2352.

• Labour induction practices in France: a population-based declarative survey in 94 maternity units. J Gynecol Obstet Hum Reprod. 2018 Feb;47(2):57-62.
• Overview of induction of labor practices in France in 2015: results of the MEDIP population-based cohort. Gynecol Obstet Fertil Senol. 2019 Jul – Aug;47(7-8):555-561.
• Comparison of effectiveness and safety of cervical ripening methods for induction of labour: A population-based study using coarsened exact matching. Paediatr Perinat Epidemiol. 2019 Sep;33(5):313-322.
• Target populations to reduce cesarean rates after induced labor: A national population-based cohort study. Acta Obstet Gynecol Scand. 2019 Oct 19.

• Providing active antenatal care depends on the place of birth for extremely preterm births: the EPIPAGE 2 cohort study. Arch Dis Child Fetal Neonatal Ed. 2017 Nov;102(6):F476-F482.
• Neonatal Outcomes in Extremely Preterm Newborns Admitted to Intensive Care after No Active Antenatal Management:A Population-Based Cohort Study. J Pediatr. 2018 Dec;203:150-155.

• Unit policies and breast milk feeding at discharge of very preterm infants: The EPIPAGE-2 cohort study. Paediatr Perinat Epidemiol. 2019 Jan;33(1):59-69.
• The impact of neonatal unit policies on breast milk feeding at discharge of moderate preterm infants: The EPIPAGE-2 cohort study. Matern Child Nutr. 2019 Oct;15(4):e12875.

• Very low prevalence of iron deficiency among young French children: a national cross-sectional survey. Matern Child Nutr. 2018 Jan; 14(1)
• Stability of serum ferritin measured by immunoturbidimetric assay after storage at -80°C for several years. PLoS One. 2017 Dec 11; 12(12).
• Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort. Acta Paediatr. 2018 Dec 7.

• Placental Complications and Bronchopulmonary Dysplasia: EPIPAGE-2 Cohort Study. Pediatrics. 2016;137:e20152163.
• Histologic Chorioamnionitis and Bronchopulmonary Dysplasia in Preterm Infants: The Epidemiologic Study on Low Gestational Ages 2 Cohort. J Pediatr. 2017;187:98-104.e3.

• Are risk factors for live singleton preterm and early term birth the same? A population-based study in France. [in press at BMJ Open].
• International variations in the gestational age distribution of births: an ecological study in 34 high-income countries. European Journal of Public Health, ckx131, https://doi.org/10.1093/eurpub/ckx131 Epub 2017 Sept 8.
• Variations in very preterm birth rates in 30 high-income countries: are valid international comparisons possible using routine data? BJOG. 2016 Sep 10. doi: 10.1111/1471-0528.14273.
• What contributes to disparities in the preterm birth rate in European countries? Curr Opin Obstet Gynecol. 2015 Feb 17.

• Impact of Latency Duration on the Prognosis of Preterm Infants after Preterm Premature Rupture of Membranes at 24 to 32 Weeks’ Gestation: A National Population-Based Cohort Study. Pediatr. 2017 Mar;182:47-52.e2.
• Tocolysis after preterm premature rupture of membranes and neonatal outcome: a propensity-score analysis. Am J Obstet Gynecol. 2017 Apr 13. pii: S0002-9378(17)30516-1.

• Managing fever in children: a national survey of parents’ knowledge and practices in France. PLoS One 2013;8:e83469.
• Symptomatic management of fever in children: a national survey of healthcare professionals’ practices in France. PLoS One 2015;10:e0143230
• National cross-sectional study of nonsteroidal anti-inflammatory drugs use highlights differences between parents and professionals and prompts safety concerns. Acta Paediatr 2016;105:e543-e8.
• Enduring large use of acetaminophen suppositories for fever management in children: a national survey of French parents and healthcare professionals’ practices. Eur J Pediatr 2016;175:987-92.
• Fever phobia 35 years later: did we fail? Acta Paediatr 2016;105:9-10.

• The burden of venipuncture pain in neonatal intensive care units: EPIPPAIN 2, a prospective observational study. Int J Nurs Stud 2016;57:48–59.
• Epidemiology and neonatal pain management of heelsticks in intensive care units: EPIPPAIN 2, a prospective observational study. Int J Nurs Stud 2016;59: 79–88.

• Intrauterine growth restriction, head size at birth and outcome in very preterm infants. J Pediatr 2015;167:975-981.
• Effect of intra- and extrauterine growth on long term neurologic outcomes of very preterm infants. J Pediatr 2016;175:93-99.

• Risk of bacterial meningitis in children 6 to 11 months of age with a first simple febrile seizure: a retrospective, cross-sectional observational study. Acad Emerg Med 2015;22:1290-7.
• Do all children who present a complex febrile seizure need a lumbar puncture? Ann Emerg Med 2017 in press

• Does the presence of risk factors for fetal growth restriction increase the probability of antenatal detection? A French National Study. Paediatr Perinat Epidemiol. 2016;30:46-55.
• Poor effectiveness of antenatal detection of fetal growth restriction and consequences for obstetric management and neonatal outcomes: a French national study. BJOG. 2015;122:518-27.
• Gestational age at diagnosis of early onset of fetal growth restriction and impact on management and survival: a population-based cohort study. BJOG in press

• Growth monitoring: a survey of current practices of primary care paediatricians in Europe. PLoS One, 2013;8:e70871.
• Should the WHO growth charts be used in France? PLoS One, 2015;10:e0120806.
• Growth monitoring as an early detection tool: a systematic review. Lancet Diabetes Endocrinology, 2016;4:447‐56.

Retard de croissance intra-utérin chez les grands prématurés : caractéristiques et impact sur la morbidité

• Impact of fetal growth restriction on neurodevelopmental outcome at 2 years for extremely preterm infants: a single institution study. J Dev Med Child Neurol 2016;58:1249-56.
• Does the antenatal detection of fetal growth restriction (FGR) have a prognostic value for mortality and short term morbidity for very preterm infants? Results from the MOSAIC cohort. J Matern Fetal Neonatal Med 2016;29:596-601.
• Impact of fetal growth restriction on mortality and morbidity in a very preterm birth cohort. J Pediatr 2010;157:733-9

Méthodologies d’évaluation des soins: exemples des délais diagnostiques et des infections sévères chez l’enfant

• Inadequate critical appraisal of studies in systematic reviews of time to diagnosis.
  J Clin Epidemiol 2016
• Why children with severe bacterial infections die : a population-based study of determinants and consequences of suboptimal care with a special emphasis on methodological issues. PLoS One. 2014 Sep 23;9(9):e10728
• Quality of reporting of studies evaluating time to diagnosis: a systematic review in paediatrics. Arch Dis Child 2014;99:244-50

Mortalité maternelle en France: profil épidémiologique, déterminants, amélioration de la mesure

• Pitfalls of national routine death statistics for maternal mortality study. Paediatr Perinat Epidemiol 2014;28:479-88.
• Ten years of confidential inquiries into maternal deaths in France, 1998-2007. Obstet Gynecol 2013;122:752-60.
• Understanding regional differences in maternal mortality: a national case-control study in France. BJOG. 2011;119:573-81.

Hémorragie du post partum: évaluation des pratiques d’anesthésie-réanimation

• Postpartum haemorrhage in Canada and France: a population-based comparison.
  PLoS One. 2013 Jun 24;8(6):e66882.
• Transfusion practices in postpartum hemorrhage: a population-based study.
  Acta Obstet Gynecol Scand. 2013 Apr;92(4):404-13.
• Critical care and transfusion management in maternal deaths from postpartum haemorrhage.
  Eur J Obstet Gynecol Reprod Biol. 2011 Oct;158(2):183-8.

Epidémiologie des délais diagnostiques des cancers de l’enfant : distribution, déterminants et conséquences médicales et juridiques

• Time to diagnosis of Ewing tumors in children and adolescents is not associated with metastasis or survival: a prospective multicenter study of 436 patients.
  J Clin Oncol. 2014;32:1935-40.
• Evidence of increasing mortality with longer time to diagnosis of cancer: is there a paediatric exception?
  Eur J Cancer. 2014;50:864-6.
• Delays in diagnosis of paediatric cancers: a systematic review and comparison with expert testimony in lawsuits.
  Lancet Oncol. 2012;13:e445-59.
• Long time to diagnosis of medulloblastoma in children is not associated with decreased survival or with worse neurological outcome.
  PLoS One. 2012;7:e33415.
• Interval between onset of symptoms and diagnosis of medulloblastoma in children: distribution and determinants in a population-based study.
  Eur J Pediatr. 2012;171:25-32.

Stratégies diagnostiques des pharyngites de l’enfant: du test de diagnostic rapide aux règles de décision clinique

• Rapid antigen detection test for group A streptococcus in children with pharyngitis (Protocol).
  Cochrane Database of Systematic
  Reviews 2013, Issue 4. Art. No.: CD010502. DOI:10.1002/14651858.CD010502.
• Rapid-antigen detection tests for group A streptococcal pharyngitis: revisiting false-positive results using PCR testing.
  The Journal of Pediatrics. 2013;162(6):1282-1284.
• Effect of clinical spectrum, inoculum size and physician characteristics on sensitivity of a rapid antigen detection test for group A streptococcal pharyngitis.
  European Journal of Clinical Microbiology and Infectious Diseases. 2013;32(6):787-793.
• Spectrum and inoculum size effect of a rapid antigen detection test for group A streptococcus in children with pharyngitis.
  PLoS One 2012; 7(6): e39085.

Prémédication avant l’intubation néonatale

• Assessment of atropine-sufentanil-atracurium anaesthesia for endotracheal intubation: an observational study in very premature infants.BMC Pediatr. 2014 May 7;14:120.
• Two-year outcomes of a randomized controlled trial of inhaled nitric oxide in premature infants.
  Pediatrics. 2013 Sep;132(3):e695-703.
• Premedication for neonatal endotracheal intubation: results from the epidemiology of procedural pain in neonates study.
  Pediatr Crit Care Med. 2013 May;14(4):e169-75.

Santé mentale des femmes et croissance de l’enfant pendant la grossesse et jusqu’à 3 ans du post partum.

• Depression and anxiety in women during pregnancy and neonatal outcome: data from the EDEN mother-child cohort.
  Early Hum Dev. 2012;88:643-9
• Prevalence and characteristics of women reporting poor mental health during pregnancy: Findings from the 2010 French National Perinatal Survey.
  Rev Epidem Santé pub 2015;63:85-95

Mortalité maternelle dans les maternités de référence au Cameroun

• Délai de prise en charge des complications obstétricales: étude dans 7 maternités au Cameroun.
  Med Trop (Mars). 2009;69:480-4
• Use of routinely collected data to assess maternal mortality in seven tertiary maternity centers in Cameroon.
  Int J Gynaecol Obstet 2011;115:240-3.

Assistance médicale à la procréation et cardiopathies congénitales : études en population

• Assessing the role of multiple pregnancies in the association between tetralogy of Fallot and assisted reproductive techniques: a path-analysis approach.
  Orphanet J Rare Dis. 2014;9:27.
• Clinical and socioeconomic predictors of pregnancy termination for fetuses with congenital heart defects: a population-based evaluation.
  Prenat Diagn. 2013;33:179-86.
• The risk for four specific congenital heart defects associated with assisted reproductive techniques: a population-based evaluation.
  Hum Reprod. 2013;28:367-74.
• Risk of congenital heart defects associated with assisted reproductive technologies: a population-based evaluation.
  Eur Heart J. 2011;32:500-8.

De la possibilité d’étudier la morbidité maternelle sévère dans les bases de données hospitalières

• Hospital discharge data can be used for monitoring procedures and intensive care related to severe maternal morbidity.
  J Clin Epidemiol. 2011;64:1014-22.
• Le programme de médicalisation du système d’information (PMSI) – processus de production des données, validité et sources d’erreurs dans le domaine de la morbidité maternelle sévère.
  RESP, 2012 vol. 60, n° 3, 2012/06, pages 177-188
• Pregnancy-Related ICU Admissions in France: Trends in Rate and Severity, 2006-2009.
  Crit Care Med. 2015 Jan;43(1):78-86

Prise en charge médicale des grossesses à bas risque en France

• Obstetric Interventions for Low-Risk Pregnant Women in France: Do Maternity Unit Characteristics Make a Difference?
  Birth 39:3 September 2012 39:183-191.
• Durée de séjour en maternité après un accouchement par voie basse en France.
  J Gynecol Obstet Biol Reprod (Paris) 2013 42(1): 76-85.
• Potential avoidability of planned cesarean sections in a French national database.
  Acta Obstet Gynecol Scand 2014 93:905-12
• Elective induction of labour and maternal request : a national population-based study.
  BJOG 2016 123:2191-7.
  

L’impact communautaire du Chikungunya à l’île de la Réunion

• Perceived morbidity and community burden after a Chikungunya outbreak: the TELECHIK survey, a population-based cohort study.
  BMC medicine 2011;9:5.
• Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study.
  Arthritis research & therapy 2013;15(1):R9.
• Perceived morbidity and community burden of chikungunya in La Reunion.
  Médecine tropicale : revue du Corps de santé colonial 2012 Mar;72 Spec No:76-82.

Facteurs de risque d’accouchement prématuré au Chili et stratégies de prévention primaire.

• Sociodemographic characteristics of mother’s population and risk of preterm birth in Chile.
  Reprod Health. 2013;10:26.
• Trends in gestational age and birth weight in Chile, 1991-2008. A descriptive epidemiological study.
  BMC Pregnancy Childbirth. 2012;12:121.

Santé bucco-dentaire et croissance maxillaire de l’enfant

• Neonatal factors associated with alteration of palatal morphology in very preterm children: the EPIPAGE cohort study.
  Early Hum Dev 2012;88:413-20.
• Impact of social and economic characteristics on orthodontic treatment among children and teenagers in France.
  Community dentistry and oral epidemiology 2010 Apr;38(2):171-9.

Développement d’un auto-questionnaire pour le diagnostic des douleurs pelviennes aigues

• Is a standardized questionnaire useful for tubal rupture screening in patients with ectopic pregnancy?
  Academic emergency medicine: official journal of the Society for Academic Emergency Medicine 2012 Jan;19(1):24-30.
• Does this woman have adnexal torsion?
  Hum Reprod 2012 Aug;27(8):2359-64.
• Triage using a self-assessment questionnaire to detect potentially life-threatening emergencies in gynecology.
  World journal of emergency surgery : WJES 2014;9:46.

Lésions cérébrales en période néonatale et devenir de l’enfant grand prématuré aux âges de 5 et 8 ans

• Predictors of the risk of cognitive deficiency in very preterm infants: the EPIPAGE prospective cohort.
  Acta Paediatr. 2011;100:370-8.
• Predictors of cerebral palsy in very preterm infants: the EPIPAGE prospective population-based cohort study.
  Dev Med Child Neurol. 2010;52:e119-25.

Développement cognitif des prématurés, Epipage

• The influence of fetal growth reference standards on assessment of cognitive and academic outcomes of very preterm children.
  The Journal of pediatrics 2012 Dec;161(6):1053-8.
• Prediction for very preterm children: also for favourable neurodevelopmental outcome.
  Acta Paediatr 2012 Jul;101(7):e267-8.
• Very preterm children free of disability or delay at age 2: predictors of schooling at age 8: a population-based longitudinal study.
  Early human development 2011 Apr;87(4):297-302.

Grossesse et santé bucco-dentaire

• Maternal dental caries and pre-term birth: results from the EPIPAP study.
  Acta Odontologica Scandinavica 2011 Jul;69(4):248-56.
• Frequency and risk indicators of tooth decay among pregnant women in France: a cross-sectional analysis.
  PloS one 2012;7(5):e33296.
• Perceived oral health and use of dental services during pregnancy: the MaterniDent study.
  Santé publique (Vandoeuvre-les-Nancy, France) 2013 May-Jun;25(3):281-92.

Distinction des méningites bactériennes et virales de l’enfant aux urgences

• Sensitivity of the bacterial meningitis score in 889 children with bacterial meningitis.
  The Journal of pediatrics 2008 Mar;152(3):378-82.
• Distinguishing between bacterial and aseptic meningitis in children: European comparison of two clinical decision rules.
  Archives of disease in childhood 2010 Dec;95(12):963-7.
• Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children: a European multicenter case cohort study.
  Archives of pediatrics & adolescent medicine 2008 Dec;162(12):1157-63.
• Clinical decision rules for evaluating meningitis in children.
  Current opinion in neurology 2009 Jun;22(3):288-93.

Le réseau périnatal de l’est parisien (2008-2010): de l’évaluation des besoins à l’évaluation des résultats

• Le réseau périnatal de l’Est parisien (2008-2010). Définition de la population concernée pour évaluer les besoins à couvrir par le réseau.
  Rev Epidemiol Santé Publique 2010 ; 58 : 127-138
• From knowledge to planning considerations: a matrix to assess health needs for the perinatal network in eastern Paris.
  Eur J Public Health. 2011 ; 21 : 504-511

Facteurs associés à l’initiation et à la durée de l’allaitement maternel en France et en Europe

• Differential trends in breastfeeding according to maternal and hospital characteristics: results from the French National Perinatal Surveys.
  Acta Paediatr. 2007;96:1290-5.
• Allaitement maternel exclusif et allaitement partiel en maternité: la situation en France en 2003.
  Arch Pediatr. 2008;15:1407-15.
• Variations in breastfeeding rates for very preterm infants between regions and neonatal units in Europe: results from the MOSAIC cohort.
  Arch Dis Child Fetal Neonatal Ed. 2011;96:F450-2.
• Evaluating regional differences in breast-feeding in French maternity units: a multi-level approach.
  Public Health Nutr. 2010;13:1946-54.

Impact des pratiques obstétricales sur l’incontinence urinaire de la femme de la grossesse à la ménopause

Thèse sur publications

Influence des caractéristiques de la structure de soin sur la prise en charge obstétricale des femmes à bas risque en France

• Level of perinatal care of the maternity unit and rate of cesarean in low-risk nulliparas.
  Obstet Gynecol. 2006;107:1269-77.
• Elective induction of labor: failure to follow guidelines and risk of cesarean delivery.
  Acta Obstet Gynecol Scand. 2007;86:657-65.
• Factors associated with the choice of delivery without epidural analgesia in women at low risk in France.
  Birth. 2008;35:171-8.
• The influence of level of care on admission to neonatal care for babies of low-risk nullipara.
  Eur J Obstet Gynecol Reprod Biol. 2009;144:21-6.